Daily Use Of Aspirin Increases Risk Of Bleeds And Death

Taking aspirin to prevent heart attacks or strokes puts the elderly at far greater risk of potentially deadly internal bleeding than first thought a study claims

Long-term daily use of aspirin may be more risky for elderly patients than previously thought, new research suggests.

Professor Peter Rothwell, of the University of Oxford, said: "We have known for some time aspirin increases the risk of bleeding for elderly patients".

In a statement, Rothwell said that "We have known for some time that aspirin increases the risk of bleeding in elderly patients".

Professor Helen Stokes-Lampard, Chair of the Royal College of Global Positioning System, said: "Aspirin is known to be an affordable and effective drug for patients who have suffered a stroke or heart attack, but we have known for some time that there are risks involved with its long-term use - and this research shows, it is particularly the case for our older patients".

Older people who take aspirin to prevent a recurrent cardiovascular event should take a proton-pump inhibitor to lower their risk of serious bleeding complications. Regardless of age, nobody should suddenly stop taking aspirin without speaking to their doctor'.

Worryingly, this advice was based on trials involving younger patients for just two to four years.

The study followed 3,166 patients in the United Kingdom who had previously had a stroke or heart attack and were prescribed antiplatelet drugs (mostly aspirin).

During the course of the study, it was noted that a total of 314 patients were admitted to hospital for internal bleeding.The risk of bleeding increased sharply with age. The study found the risk of fatal or disabling bleeding only increased with age and the outcome worsened for older patients who suffered non-fatal bleeds. For patients under the age of 65, the annual rate of hospital admissions was 1.5 percent; for patients between the age of 75 to 84, the rate rose to 3.5 percent; and for those over the age of 85 it was five percent.

YouTube Star Austin Jones Arrested on Child Pornography Charges
He was arrested at O'Hare International Airport in Chicago, Illinois, and will appear in court for his bond hearing on Wednesday. On Monday night, YouTube star Austin Jones was arrested and charged with two counts of production of child pornography.

"While there is some evidence that PPIs might have some small long-term risks, this study shows that the risk of bleeding without them at older ages is high, and the consequences significant".

Scientists suggest that to reduce these risks, older people should also take stomach-protecting PPI pills.

The authors believe the low uptake of PPIs is partly due to their side effects, but also to previous underestimations of the risk of bleed. "Prescription of any drug is a balance between the benefits of the medication against its risks, and aspirin is no different", he said.

The painkiller is often prescribed to help prevent heart disease and strokes in those patients deemed to be most at risk.

The risk of internal bleeding caused by swallowing the blood-thinning pills is far higher in this group of patients than was previously thought, new research shows. He added that cardiologists and neurologists are influenced more by what they see in practice than what they read in the data, meaning these specialists may not fully realize the risks of aspirin.

Half the patients were 75 or older at the start of the period covered by the study.

'In the over-75s the risk is higher - but the key point is that this risk is substantially preventable by taking proton pump inhibitors alongside aspirin'. "Therefore, any uncertainty about the small risks of PPI use are very likely to be outweighed by the benefits", said Professor Rothwell.

Related News:

  • Uber changes ahead as another member of core leadership team departs

    The changes would also further destabilise the leadership at Uber, which has upended the transportation industry worldwide. He made headlines in 2014 for suggesting Uber could do opposition research on journalists who were critical of the company.
    Saudi king to meet Iraqi PM as regional tensions at high

    Saudi king to meet Iraqi PM as regional tensions at high

    Saudi Arabia, the UAE and Bahrain accuse Qatar of supporting terrorism networks in the region. The Daesh Takfiri terrorist group has claimed responsibility for the attacks.
    Former Penn State president gets jail time for failing to report Sandusky

    Former Penn State president gets jail time for failing to report Sandusky

    Curley and Schultz were arrested in 2011, and Spanier in 2012. "Why no one made a phone call to police ... is beyond me". Former athletic director Timothy Curley, 63, was sentenced to seven to 23 months incarceration and two years probation.
  • Crude Oil Inventory Spread Is Rising: The Impact on Oil Prices

    US West Texas Intermediate ( WTI ) crude futures were at $45.94 per barrel, down 52 cents, or 1.1 per cent. Meanwhile, crude oil continues to trade close to the $46 per barrel mark.

    Bill Cosby admits he apologised to accuser's mother over alleged assault

    Testimony revealed Benadryl did come in a blue pill around that time. "It can cause significant sedation". Although Valliere admitted to writing them, the judge ultimately refused the request for a dismissal.

    'Wonder Woman' has biggest opening ever for a female director

    I like to think we've come a long way since the 1920's, but mankind still surprises me with a curveball from time to time. Baroness Paula von Gunther was created by William Moulton Marston as the first recurring enemy of Wonder Woman .
  • Keshia Knight Pulliam speaks on Cosby loyalty on 'Today'

    Keshia Knight Pulliam speaks on Cosby loyalty on 'Today'

    Jurors are now well into their third day of deliberations in the trial of entertainer Bill Cosby on sexual assault charges. The jury is weighing three counts of aggravated indecent assault against Cosby , each carrying a maximum 10-year sentence.
    Kathy Griffin FIRED over Donald Trump joke

    Kathy Griffin FIRED over Donald Trump joke

    They continued: "We found what she did disgusting and offensive". " Kathy Griffin should be ashamed of herself", Trump wrote. The announcement came after Griffin made a public apology to her followers, admitting that she had gone "way too far".
    Puerto Rico mulls political status in new referendum

    Puerto Rico mulls political status in new referendum

    However, the results of these referendums were hardly reliable due to fact that most results favor whichever party was in power. Thousands of Puerto Ricans serve in the US military but can not vote for their commander in chief.
  • Congressional Investigators Seek Tapes, Notes On Trump-Comey Conversations

    Trump has knocked off some Obama regulations via executive orders, but no major legislation has come out of Congress . President Trump's picking and choosing which parts of James Comey's testimony he says are true, and which are false.

    North Korea says it has tested new anti-ship missile

    Pyongyang often accuses Seoul of kidnapping its citizens and forcing them to defect to the South . South Korea's military says the missiles flew some 200 kilometres.
    Trump's top lawyer to face questions on Russia, Comey

    Trump's top lawyer to face questions on Russia, Comey

    Attorney General Jeff Sessions said reports suggesting he had a third meeting with Russian ambassador Sergey Kislyak are false. On Thursday, Comey said there were some things he couldn't discuss because they involved classified information.


Most liked

Aston Martin launches race-inspired Vantage AMR models
These are people who love our cars for their motorsport pedigree, and for their unmistakable dynamic and emotional qualities. Priced from £97,995 for the basic V8 coupe, deliveries are due to commence in the last quarter of this year.

Apple Now Allows Users to Tip with In-App Purchases
Mobile analytics firm Sensor Tower estimates the app has generated about $80,000 per month. Currently, Apple doesn't have a filtering or approval process for search ads.

Sony Defends Blocking PS4 Cross-Play With Xbox & Nintendo
There was no mention of the Xbox One X console unveiled a day earlier by rival Microsoft in a heightened challenge to PS4. As an additional added perk, Minecraft is throwing in a server browser to its latest update .

Haas cuts Federer comeback short in Stuttgart
Federer reckons his rival, yet good friend, could well finish top of the rankings at the end of the year. The failure represents just the fifth loss of the season for the icon who sits at No. 5 in the world .

North Korea frees American student; parents say he's in coma
Death while in captivity would have yielded no concessions for North Korea from Kim's perspective, according to the report. Yun insisted on Warmbier's immediate release on humanitarian grounds, officials said, and the North Koreans agreed.

Verizon Completes Yahoo Deal, Marissa Mayer Exits
Yahoo's stake in the e-commerce giant, Alibaba, and Yahoo Japan will be diverted into a holding company called Altaba, Inc. Tim Armstrong , former CEO of AOL, is now CEO of Oath , which is part of Verizon's Media and Telematics organization.

Minecraft is getting a graphics upgrade
Simultaneously with the release of Windows 10 , this operating system was released a special version of the game rewritten in C++. Saved data, purchased content, and world progress will transfer over from the older versions of the game to the new one.

Comey says Trump fired him to undermine FBI Russia investigation
Comey claimed the President privately told him, "I hope you can see your way clear to letting this go, to letting Flynn go". As I explained in March, it seems very unlikely that the always-sanguine former President Obama would bring such a suit.

Uber board adopts all recommendations from Eric Holder investigation
Holder's report is said to focus on the company's culture and structure, making recommendations at a macro level. Eric Alexander , who oversaw business in Asia, departed amid reports of the India rape controversy last week .

Tornadoes, hail hit eastern Wyoming; 1 injury reported
According to the family, the cattle shed was picked up and tossed by the storm's high winds, leaving just one wall standing. Strong winds, hail, and tornadoes are possible in areas stretching from Fargo, North Dakota to Wichita, Kansas.

AG Sessions wants Senate testimony to be public
The president has also criticized the Justice Department's failed efforts to defend his travel ban in federal court. Sessions could be asked about that part of Comey's testimony, as well as his role in Comey's firing last month.

House intel panel approves subpoenas for Flynn, Trump lawyer Cohen
The subpoenas mark new signs of life in the House committee's investigation, which seemed to stall after Comey's testimony. Republicans have implied the unmasking of Trump associates could have been politically motivated.

PlayerUnknown reveals climbing and vaulting mechanics, weather changes coming to Battlegrounds
You'll climb fences, vault over low walls, jump out of windows and even roll over a auto like it's a buddy cop movie. The movement changes are big, and you can see their effects below.

Senate GOP, Dems agree on new sanctions on Russia
It also allows new penalties on key elements of the Russian Federation economy, including mining, metals, shipping and railways. The step is supported by both Republicans and Democrats, and the vote is set to take place on Thursday, RIA Novosti reported .

Attorney General Sessions to face US Senate panel in public
Former White House press secretary Ari Fleischer advised Trump to "stop talking" Sunday before he finds himself in legal trouble. If he confirms there was a meeting at which he and Kushner were asked to leave, it could bolster Comey's account.